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Ageing skin is one of the things that
people do not want. As soon as there
are signs of these on a person’s
face, using Retin-A is effective in
removing them. There is believed to
be significant difference visible
when one uses Retin-A, and it is expected
that after using the medicine for
at least 3 weeks wrinkles begin to
diminish.
Ingredients:
The chief ingredient in Retin-A is
Tretinoin: it is a yellow or light
orange crystalline powder. It has
an odor that is quite different because
of its floral effect. Tretinoin dissolves
in dimethylsulfoxide. It is slightly
soluble in polyethylene glycol 400,
and is completely soluble in 100%
ethanol. Tretinoin does not dissolve
in water and mineral oil and glycerin.
Tretinoin’s chemical name is
(all-E)-3,7?dimethyl-9?(2,6,6?trimethyl-1?cyclonexen-1?yl)-2,4,6,8?nonatetraenoic
acid. It is also known as all-trans?retinoic
acid (C20H28O2; molecular weight 300.44
vitamin A acid.
Chemistry:
Though the main ingredient of Retin-A
is in a crystalline powdered form
(Tretinoin), Retin-A is available
in the form of a Cream, Gel and Liquid.
All three applications may be used
to treat acne vulgaris.
Retin-A Gel has the main ingredient
(retinoic acid, vitamin A acid) in
two possible strengths; either it
will be in 0.025% or 0.01% by weight.
It will also be in a gel of hydroxypropyl
cellulose, butylated hydroxytoluene
and alcohol 90% w/w.
Retin-A cream that contains retuning,
has the ingredient in three types
of strengths: 0.1%, 0.05%, or 0.025%
by weight. It is in a hydrophilic
cream consisting of:
• satiric acid,
• isopropyl microstate,
• polyoxyl 40 stearate,
• stearyl alcohol,
• xanthan gum,
• sorbic acid,
• butylated hydroxytoluene,
• purified water.
Retin-A Liquid consists
of tretinoin with a 0.05% weight,
butylated hydroxytoluene, polyethylene
glycol 400 and alcohol.
Dosage:
You are not advised to use Retin-A
Drug with other skin products that
contains alcohol. This is because
of the alcohol interference that could
take place.
You should not use Retin-A with skin
products that contain any of the following
ingredients:
• sulfur,
• salicylic acid,
• resorcinol.
These ingredients can lead
to drying and irritation to the skin.
• If you happen
to miss out on a dose of Retin-A,
you should take the missed dose as
soon as you think of it. Also remember
that it is pointless to go ahead with
a missed dose when it is almost time
for your next dose. Do not "double-up"
and take both doses close together
• You should not use Retin-A
if you have a rash that has been caused
by exfoliant or keratolytic treatments.
• You need to remove all make
up before using Retin-A.
• In case you are pregnant or
plant to get pregnant you should consult
your doctor first.
• Retin-A is not to be left
around children, as it is something
that should not go in one’s
eyes, mouth or open sores. It should
also be stored away at room temperature
and not be exposed to sunlight. |
