Ingredients,
Chemistry, Dosage
Flanose is a medication for
treating Nasal blockage and
infection. It has the ability
to deal with inflammation, through
which it can reduce symptoms
of nasal allergies.
Ingredients:
The active ingredient in Flonase
is Fluticasone Propionate. It
is an artificial corticosteroid
with the following chemical
name: S-(fluoromethyl)6a,9-difluoro-11ß-17-dihydroxy-16a-methyl-3-oxoandrosta-
1,4-diene-17ß-carbothioate,
17-propionate.
In addition to containing microfine
fluticasone propionate, Flonase
also contains microcrystalline
cellulose and carboxymethylcellulose
sodium, polysorbate 80, dextrose,
0.02% w/w benzalkonium chloride,
and 0.25% w/w phenylethyl alcohol.
Chemistry:
Fluticasone propionate in appearance
is a white or off-white powder.
It has a molecular weight of
500.6, and an empirical formula:
C25H31F3O5S.
Fluticasone propionate is not
soluble in water, but is readily
soluble in dimethyl sulfoxide
and dimethylformamide, and only
partially soluble in 95% ethanol
and methanol.
Dosage:
Flonase is a nasal spray that
is available in an aqueous suspension
of 50 mcg (microfine fluticasone
propionate). Flonase acts directly
on the nasal mucosa and is administered
through an atomizing spray pump.
Flonase needs to be administered
by using a pump. This nasal
pump needs to be primed before
use. Actuating the pump about
five or six times is a good
idea. You should do this when
you are about to use the pump
for the first time or when you
are using it after a week or
more.
Once the pump is in action,
it delivers about 50 mcg of
fluticasone propionate per 100
mg of the medication. Also,
every 16-g FLONASE Nasal Spray
bottle delivers a total of 120
metered sprays. Beyond 120 metered
sprays, the pump should not
be used because of the fluticasone
propionate delivered not being
in correct proportion anymore
anymore.
While using Flonase
you should watch out for the
side effects given below.
Mild side effects experienced
would include: nose bleeding,
nasal burning irritation,
blood in nasal mucus,
Uncommon side effects include:
headache, sneezing, runny nose,
nasal dryness, congestion, and
stomach upset.
Some side effects that are
unlikely to occur include: vision
problems, headache, increased
thirst or urination, unusual
weakness, weight loss, nausea,
and dizziness.
If any of these side effects
do occur, you should see a doctor
immediately.
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